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Lamberts Natural Beta Carotene With Mixed Carotenoids 15mg 90 Capsules

Lamberts Natural Beta Carotene With Mixed Carotenoids 15mg 90 Capsules
£8.59  

Beta carotene is one of the best known antioxidants which helps to protect the skin against the damaging effects of ‘free radicals’ created by the action of ultra-violet rays on the skin.Lamberts Natural Beta Carotene with mixed carotenoids supplies a unique combination of important carotenoids that are found in many fruits and vegetables.Our bodies are being continually exposed to ‘free radical’ damage as a result of the environment in which we live. Air pollution and cigarette smoking are the major factors that generate ‘free radicals’, but one of the most important is the effect that sunlight has on our skin. The body has its own natural defence mechanism to fight these ‘free radicals’, substances called antioxidants which neutralise ‘free radicals’ thus helping to protect our cells from damage. Beta carotene is one of the best known antioxidants which helps to protect the skin against the damaging effects of ‘free radicals’ created by the action of ultra-violet rays on the skin.β-Caroteneis anorganic compoundand classified as aterpenoid. It is a strongly-coloured red-orangepigmentabundant in plants and fruits. As acarotenewith beta-rings at both ends, it is the most common form of carotene. It is a precursor (inactive form) ofvitamin A.The structure was deduced by Karrer et al.In nature, β-carotene is a precursor to vitamin A via the action ofbeta-carotene 15,15'-monooxygenase. β-Carotene is also the substance incarrotsthat colours them orange. β-Carotene is biosynthesized fromgeranylgeranyl pyrophosphate.Isolation of beta-carotene from fruits abundant in carotenoids is commonly done using column chromatography. The separation of beta-carotene from the mixture of carotenoids is based on the polarity of a compound. Beta-carotene is a non-polar compound, so it is separated with a non-polar solvent such ashexane.Being highlyconjugated, it is deeply colored, and as ahydrocarbonlacking functional groups, it is verylipophilic.β-Carotene contributes to the orange color of many different fruits and vegetables. Vietnamesegac(Momordica CochinchinensisSpreng.) and crudepalm oilare particularly rich sources, as are yellow and orange fruits, such asmangoesandpapayas, orangeroot vegetablessuch ascarrotsandyamsand in greenleafy vegetablessuch asspinach,kale,sweet potatoleaves, andsweet gourd leaves.Vietnamgacand crudepalm oilhave by far the highest content of β-carotene of any known fruit or vegetable, 10 times higher than carrots for example. However,Gacis quite rare and unknown outside its native region of SE Asia, and crudepalm oilis typically processed to remove the cartenoids before sale to improve the color and clarity.The average daily intake of β-carotene is in the range 2–7mg, as estimated from a pooled analysis of 500,000 women living in the USA, Canada and some European countries.The U.S. Department of Agriculture lists the following 10 foods to have the highest β-carotene content per serving.ItemGrams per servingServing sizeMilligrams β-carotene per servingMilligrams β-carotene per 100 gCarrot juice, canned2361 cup22.09.3Pumpkin, canned, without salt2451 cup17.06.9Sweet potato, cooked, baked in skin, without salt1461 potato16.811.5Sweet potato, cooked, boiled, without skin1561 potato14.79.4Spinach, frozen, chopped or leaf, cooked, boiled, drained, without salt1901 cup13.87.2Carrots, cooked, boiled, drained, without salt1561 cup13.08.3Spinach, canned, drained solids2141 cup12.65.9Sweet potato, canned, vacuum pack2551 cup12.24.8Carrots, frozen, cooked, boiled, drained, without salt1461 cup12.08.2Collards, frozen, chopped, cooked, boiled, drained, without salt1701 cup11.66.8Side EffectsThe most common side effect of excessive β-carotene consumption iscarotenodermia, a harmless condition that presents as a conspicuous orange skin tint arising from deposition of the carotenoid in the outermost layer of theepidermis. Chronic, high doses of β-carotene supplements have been associated with increased rate oflung canceramong those whosmoke.Additionally, supplemental beta-carotene may increase the risk of prostate cancer,intracerebral hemorrhage, and cardiovascular and total mortality in people who smoke cigarettes or have a history of high-level exposure to asbestos.Beta - Carotene and Lung Cancer in SmokersBeta carotene increases the probability of lung cancer in cigarette smokers. Whenretinoic acidis liganded to RAR-beta (Retinoic Acid Receptor beta), the complex bindsAP1(Activator Protein 1).AP1is a transcription factor that binds to DNA and in downstream events promote cell proliferation. Therefore, in the presence ofretinoic acid, the retinoic acid:RAR-beta complex binds toAP1and inhibit AP-1 from binding to DNA. In that case,AP1is no longer expressed, and cell proliferation does not occur. Cigarette smoke increases the asymmetric cleavage of beta-carotene, decreasing the level ofretinoic acidsignificantly. This can lead to a higher level of cell proliferation in smokers, and consequently, a higher probability of lung cancer.However, no lung damage has been detected in those who are exposed to cigarette smoke and take a physiologic dose beta-carotene (6mg) in contrast to pharmacologic dose (30mg). Therefore, theoncologyfrom beta-carotene is based on both cigarette smoke and high daily doses of beta-carotene.

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Lamberts Natural Beta Carotene With Mixed Carotenoids 15mg 90 Capsules

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Lamberts Natural Beta Carotene With Mixed Carotenoids 15mg 90 Capsules on other UK sites

Lamberts Natural Beta Carotene With Mixed Carotenoids 15mg 90 Capsules
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